The pancreas tin terminate live on triggered to regenerate itself through a type of fasting diet, state the US researchers.
Restoring the role of the organ which helps command blood refined saccharify levels, reversed symptoms of diabetes inward beast experiments.
The study, published inward the periodical Cell, says the diet reboots the body.
Experts said the findings were "potentially really exciting" every bit they could larn a novel handling for the disease.
People are nonetheless advised non to essay this without medical advice.
In the experiments, mice were set on a modified cast of the "fasting-mimicking diet". It is similar to the human cast of the diet when people pass v days on a depression calorie, depression protein, depression saccharide merely high unsaturated-fat diet.
It resembles a vegan diet amongst nuts in addition to soups, merely amongst roughly 800 to 1,100 calories a twenty-four hours for 5 days.
Then they choose 25 days eating what they want. Overall it mimics periods of feast in addition to famine.
Previous enquiry has suggested it tin terminate tedious the footstep of ageing.
Diabetes therapy?
Animal experiments showed the diet regenerated a particular type of jail cellphone inward the pancreas called a beta cell.
These are the cells that respect refined saccharify inward the blood in addition to unloosen the hormone insulin if it gets also high.
Dr Valter Longo, from the University of Southern California, said: "Our determination is that past times pushing the mice into an extreme Earth in addition to and hence bringing them back, past times starving them in addition to and hence feeding them again, the cells inward the pancreas are triggered to exercise some variety of developmental reprogramming that rebuilds the component subdivision of the organ that's no longer functioning."
There were benefits inward both type 1 in addition to type ii diabetes inward the mouse experiments.
Type 1 is caused past times the immune arrangement destroying beta cells in addition to type ii is largely caused past times lifestyle in addition to the torso no longer responding to insulin.
Further tests on tissue samples from people amongst type 1 diabetes produced similar effects.
Dr Longo said: "Medically, these findings choose the potential to live on really of import because we've shown, at to the lowest degree inward mouse models that you lot tin terminate exercise diet to contrary the symptoms of diabetes.
"Scientifically, the findings are maybe fifty-fifty to a greater extent than of import because we've shown that you lot tin terminate exercise diet to reprogram cells without having to brand whatsoever genetic alterations."
What's it like?
BBC reporter Peter Bowes took component subdivision inward a split lawsuit amongst Dr Valter Longo.
He said: "During each five-day fasting cycle, when I ate virtually a quarter of the average person's diet, I lost betwixt 2kg in addition to 4kg (4.4-8.8lbs).
"But earlier the side past times side bike came round, 25 days of eating ordinarily had returned me almost to my master weight.
"But non all consequences of the diet faded hence quickly."
His blood pressure level was lower every bit was a hormone called IGF-1, which is linked to some cancers.
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